| Guaynabo to Superior (Colorado) | 2,754.33 mi (4,432.67 km) |
| Guaynabo to Superior (Wisconsin) | 2,449.04 mi (3,941.36 km) |
| Guaynabo to Surprise (Arizona) | 3,035.86 mi (4,885.74 km) |
| Guaynabo to Susanville (California) | 3,550.69 mi (5,714.29 km) |
| Guaynabo to Sussex (Wisconsin) | 2,141.55 mi (3,446.50 km) |
| Guaynabo to Suwanee (Georgia) | 1,547.63 mi (2,490.67 km) |
| Guaynabo to Swansea (Illinois) | 1,998.98 mi (3,217.05 km) |
| Guaynabo to Sweetwater (Florida) | 1,045.29 mi (1,682.23 km) |
| Guaynabo to Sweetwater (Texas) | 2,337.13 mi (3,761.25 km) |
| Guaynabo to Sycamore (Illinois) | 2,102.37 mi (3,383.44 km) |
| Guaynabo to Sylacauga (Alabama) | 1,611.87 mi (2,594.05 km) |
| Guaynabo to Sylvania (Ohio) | 1,916.25 mi (3,083.90 km) |
| Guaynabo to Syosset (New York) | 1,610.67 mi (2,592.13 km) |
| Guaynabo to Syracuse (New York) | 1,801.63 mi (2,899.44 km) |
| Guaynabo to Syracuse (Utah) | 3,123.70 mi (5,027.11 km) |
