| Guaynabo to St. George (Utah) | 3,137.66 mi (5,049.57 km) |
| Guaynabo to St. Helens (Oregon) | 3,724.42 mi (5,993.88 km) |
| Guaynabo to St. James (New York) | 1,609.14 mi (2,589.67 km) |
| Guaynabo to St. John (Indiana) | 2,031.05 mi (3,268.65 km) |
| Guaynabo to St. Joseph (Missouri) | 2,259.17 mi (3,635.78 km) |
| Guaynabo to St. Louis (Missouri) | 2,013.69 mi (3,240.72 km) |
| Guaynabo to St. Louis Park (Minnesota) | 2,413.26 mi (3,883.77 km) |
| Guaynabo to St. Marys (Georgia) | 1,291.32 mi (2,078.18 km) |
| Guaynabo to St. Marys (Pennsylvania) | 1,754.82 mi (2,824.11 km) |
| Guaynabo to St. Matthews (Kentucky) | 1,806.89 mi (2,907.91 km) |
| Guaynabo to St. Michael (Minnesota) | 2,436.73 mi (3,921.55 km) |
| Guaynabo to St. Paul (Minnesota) | 2,403.56 mi (3,868.15 km) |
| Guaynabo to St. Peter (Minnesota) | 2,408.50 mi (3,876.10 km) |
| Guaynabo to St. Peters (Missouri) | 2,035.33 mi (3,275.54 km) |
| Guaynabo to St. Petersburg (Florida) | 1,234.67 mi (1,987.01 km) |
