| Guaynabo to Seymour (Tennessee) | 1,618.99 mi (2,605.52 km) |
| Guaynabo to Shady Hills (Florida) | 1,248.94 mi (2,009.98 km) |
| Guaynabo to Shafter (California) | 3,432.01 mi (5,523.29 km) |
| Guaynabo to Shaker Heights (Ohio) | 1,837.18 mi (2,956.66 km) |
| Guaynabo to Shakopee (Minnesota) | 2,409.63 mi (3,877.93 km) |
| Guaynabo to Sharon (Pennsylvania) | 1,793.29 mi (2,886.02 km) |
| Guaynabo to Sharonville (Ohio) | 1,811.79 mi (2,915.80 km) |
| Guaynabo to Shasta Lake (California) | 3,644.91 mi (5,865.91 km) |
| Guaynabo to Shawnee (Kansas) | 2,231.34 mi (3,591.00 km) |
| Guaynabo to Shawnee (Oklahoma) | 2,219.24 mi (3,571.53 km) |
| Guaynabo to Sheboygan (Wisconsin) | 2,155.21 mi (3,468.47 km) |
| Guaynabo to Shelby (North Carolina) | 1,502.32 mi (2,417.76 km) |
| Guaynabo to Shelbyville (Indiana) | 1,874.83 mi (3,017.24 km) |
| Guaynabo to Shelbyville (Kentucky) | 1,788.92 mi (2,878.99 km) |
| Guaynabo to Shelbyville (Tennessee) | 1,715.68 mi (2,761.11 km) |
