| Guaynabo to Scottsboro (Alabama) | 1,661.46 mi (2,673.86 km) |
| Guaynabo to Scottsdale (Arizona) | 3,002.58 mi (4,832.18 km) |
| Guaynabo to Scranton (Pennsylvania) | 1,687.71 mi (2,716.10 km) |
| Guaynabo to Seabrook (Maryland) | 1,561.99 mi (2,513.78 km) |
| Guaynabo to Seabrook (Texas) | 1,974.85 mi (3,178.22 km) |
| Guaynabo to Seaford (New York) | 1,600.80 mi (2,576.23 km) |
| Guaynabo to Seagoville (Texas) | 2,127.23 mi (3,423.45 km) |
| Guaynabo to Seal Beach (California) | 3,357.25 mi (5,402.97 km) |
| Guaynabo to Searcy (Arkansas) | 1,952.54 mi (3,142.31 km) |
| Guaynabo to Seaside (California) | 3,584.83 mi (5,769.23 km) |
| Guaynabo to SeaTac (Washington) | 3,722.77 mi (5,991.23 km) |
| Guaynabo to Seattle (Washington) | 3,726.61 mi (5,997.41 km) |
| Guaynabo to Sebastian (Florida) | 1,119.04 mi (1,800.92 km) |
| Guaynabo to Sebring (Florida) | 1,159.15 mi (1,865.48 km) |
| Guaynabo to Secaucus (New Jersey) | 1,617.82 mi (2,603.64 km) |
