| Guaynabo to Santa Rosa (California) | 3,644.67 mi (5,865.52 km) |
| Guaynabo to Santaquin (Utah) | 3,089.03 mi (4,971.31 km) |
| Guaynabo to Santee (California) | 3,289.61 mi (5,294.12 km) |
| Guaynabo to Sapulpa (Oklahoma) | 2,194.13 mi (3,531.11 km) |
| Guaynabo to Saraland (Alabama) | 1,622.56 mi (2,611.27 km) |
| Guaynabo to Sarasota (Florida) | 1,213.45 mi (1,952.86 km) |
| Guaynabo to Sarasota Springs (Florida) | 1,208.76 mi (1,945.31 km) |
| Guaynabo to Saratoga (California) | 3,600.07 mi (5,793.75 km) |
| Guaynabo to Saratoga Springs (New York) | 1,763.30 mi (2,837.76 km) |
| Guaynabo to Saratoga Springs (Utah) | 3,102.04 mi (4,992.24 km) |
| Guaynabo to Sartell (Minnesota) | 2,474.94 mi (3,983.04 km) |
| Guaynabo to Satellite Beach (Florida) | 1,140.03 mi (1,834.70 km) |
| Guaynabo to Sauk Rapids (Minnesota) | 2,471.56 mi (3,977.58 km) |
| Guaynabo to Sault Ste. Marie (Michigan) | 2,202.08 mi (3,543.90 km) |
| Guaynabo to Savage (Minnesota) | 2,404.48 mi (3,869.63 km) |
