| Guaynabo to Sanford (Maine) | 1,751.22 mi (2,818.32 km) |
| Guaynabo to Sanford (North Carolina) | 1,426.54 mi (2,295.79 km) |
| Guaynabo to Sanger (California) | 3,460.55 mi (5,569.22 km) |
| Guaynabo to Santa Ana (California) | 3,346.30 mi (5,385.34 km) |
| Guaynabo to Santa Barbara (California) | 3,455.01 mi (5,560.30 km) |
| Guaynabo to Santa Clara (California) | 3,597.48 mi (5,789.59 km) |
| Guaynabo to Santa Clara (Oregon) | 3,718.30 mi (5,984.03 km) |
| Guaynabo to Santa Clarita (California) | 3,385.43 mi (5,448.33 km) |
| Guaynabo to Santa Cruz (California) | 3,598.76 mi (5,791.64 km) |
| Guaynabo to Santa Fe (New Mexico) | 2,704.19 mi (4,351.98 km) |
| Guaynabo to Santa Fe (Texas) | 1,975.68 mi (3,179.55 km) |
| Guaynabo to Santa Fe Springs (California) | 3,357.79 mi (5,403.84 km) |
| Guaynabo to Santa Maria (California) | 3,498.60 mi (5,630.46 km) |
| Guaynabo to Santa Monica (California) | 3,382.21 mi (5,443.14 km) |
| Guaynabo to Santa Paula (California) | 3,417.40 mi (5,499.77 km) |
