| Grosse Pointe Woods to Superior (Colorado) | 1,166.89 mi (1,877.93 km) |
| Grosse Pointe Woods to Superior (Wisconsin) | 538.81 mi (867.13 km) |
| Grosse Pointe Woods to Surprise (Arizona) | 1,707.16 mi (2,747.40 km) |
| Grosse Pointe Woods to Susanville (California) | 1,942.67 mi (3,126.42 km) |
| Grosse Pointe Woods to Sussex (Wisconsin) | 274.19 mi (441.26 km) |
| Grosse Pointe Woods to Suwanee (Georgia) | 582.85 mi (938.01 km) |
| Grosse Pointe Woods to Swansea (Illinois) | 458.82 mi (738.39 km) |
| Grosse Pointe Woods to Sweetwater (Florida) | 1,159.82 mi (1,866.56 km) |
| Grosse Pointe Woods to Sweetwater (Texas) | 1,177.98 mi (1,895.78 km) |
| Grosse Pointe Woods to Sycamore (Illinois) | 297.45 mi (478.70 km) |
| Grosse Pointe Woods to Sylacauga (Alabama) | 665.35 mi (1,070.78 km) |
| Grosse Pointe Woods to Sylvania (Ohio) | 65.18 mi (104.89 km) |
| Grosse Pointe Woods to Syosset (New York) | 497.78 mi (801.10 km) |
| Grosse Pointe Woods to Syracuse (New York) | 345.22 mi (555.59 km) |
| Grosse Pointe Woods to Syracuse (Utah) | 1,498.93 mi (2,412.29 km) |
