| Grosse Pointe Woods to Storm Lake (Iowa) | 625.65 mi (1,006.88 km) |
| Grosse Pointe Woods to Storrs (Connecticut) | 547.01 mi (880.33 km) |
| Grosse Pointe Woods to Stoughton (Wisconsin) | 322.89 mi (519.64 km) |
| Grosse Pointe Woods to Stow (Ohio) | 115.18 mi (185.37 km) |
| Grosse Pointe Woods to Streamwood (Illinois) | 271.57 mi (437.05 km) |
| Grosse Pointe Woods to Streator (Illinois) | 318.67 mi (512.85 km) |
| Grosse Pointe Woods to Streetsboro (Ohio) | 115.03 mi (185.12 km) |
| Grosse Pointe Woods to Strongsville (Ohio) | 95.10 mi (153.05 km) |
| Grosse Pointe Woods to Stuart (Florida) | 1,063.58 mi (1,711.67 km) |
| Grosse Pointe Woods to Stuarts Draft (Virginia) | 366.92 mi (590.51 km) |
| Grosse Pointe Woods to Sturgis (Michigan) | 136.44 mi (219.57 km) |
| Grosse Pointe Woods to Suamico (Wisconsin) | 300.13 mi (483.01 km) |
| Grosse Pointe Woods to Sudley (Virginia) | 379.14 mi (610.16 km) |
| Grosse Pointe Woods to Suffern (New York) | 460.14 mi (740.52 km) |
| Grosse Pointe Woods to Suffolk (Virginia) | 517.85 mi (833.40 km) |
