| Grosse Pointe Woods to Smyrna (Delaware) | 438.26 mi (705.31 km) |
| Grosse Pointe Woods to Smyrna (Georgia) | 598.81 mi (963.69 km) |
| Grosse Pointe Woods to Smyrna (Tennessee) | 487.15 mi (783.98 km) |
| Grosse Pointe Woods to Snellville (Georgia) | 595.87 mi (958.95 km) |
| Grosse Pointe Woods to Snoqualmie (Washington) | 1,914.57 mi (3,081.20 km) |
| Grosse Pointe Woods to Snyder (Texas) | 1,189.46 mi (1,914.25 km) |
| Grosse Pointe Woods to Socastee (South Carolina) | 640.30 mi (1,030.47 km) |
| Grosse Pointe Woods to Socorro (Texas) | 1,481.55 mi (2,384.33 km) |
| Grosse Pointe Woods to Soddy-Daisy (Tennessee) | 510.88 mi (822.19 km) |
| Grosse Pointe Woods to Solana Beach (California) | 1,972.21 mi (3,173.97 km) |
| Grosse Pointe Woods to Soledad (California) | 2,074.35 mi (3,338.34 km) |
| Grosse Pointe Woods to Solon (Ohio) | 104.35 mi (167.94 km) |
| Grosse Pointe Woods to Somers Point (New Jersey) | 483.57 mi (778.23 km) |
| Grosse Pointe Woods to Somerset (Kentucky) | 380.86 mi (612.94 km) |
| Grosse Pointe Woods to Somerset (New Jersey) | 454.48 mi (731.41 km) |
