| Grosse Pointe Woods to Silver Firs (Washington) | 1,927.37 mi (3,101.80 km) |
| Grosse Pointe Woods to Silver Spring (Maryland) | 388.47 mi (625.18 km) |
| Grosse Pointe Woods to Silver Springs Shores (Florida) | 921.92 mi (1,483.68 km) |
| Grosse Pointe Woods to Silverdale (Washington) | 1,953.00 mi (3,143.05 km) |
| Grosse Pointe Woods to Silverton (Oregon) | 1,979.23 mi (3,185.27 km) |
| Grosse Pointe Woods to Simi Valley (California) | 2,006.32 mi (3,228.86 km) |
| Grosse Pointe Woods to Simpsonville (South Carolina) | 533.69 mi (858.89 km) |
| Grosse Pointe Woods to Sioux City (Iowa) | 686.92 mi (1,105.49 km) |
| Grosse Pointe Woods to Sioux Falls (South Dakota) | 702.43 mi (1,130.44 km) |
| Grosse Pointe Woods to Skokie (Illinois) | 249.16 mi (400.99 km) |
| Grosse Pointe Woods to Sleepy Hollow (New York) | 474.10 mi (763.00 km) |
| Grosse Pointe Woods to Slidell (Louisiana) | 921.79 mi (1,483.47 km) |
| Grosse Pointe Woods to Smithfield (North Carolina) | 536.94 mi (864.12 km) |
| Grosse Pointe Woods to Smithfield (Utah) | 1,475.55 mi (2,374.67 km) |
| Grosse Pointe Woods to Smithville (Missouri) | 644.27 mi (1,036.85 km) |
