| Grosse Pointe Woods to Orangevale (California) | 2,010.89 mi (3,236.22 km) |
| Grosse Pointe Woods to Orchards (Washington) | 1,960.20 mi (3,154.64 km) |
| Grosse Pointe Woods to Orcutt (California) | 2,072.92 mi (3,336.04 km) |
| Grosse Pointe Woods to Oregon (Ohio) | 60.70 mi (97.69 km) |
| Grosse Pointe Woods to Oregon (Wisconsin) | 331.31 mi (533.20 km) |
| Grosse Pointe Woods to Oregon City (Oregon) | 1,966.56 mi (3,164.88 km) |
| Grosse Pointe Woods to Orem (Utah) | 1,493.50 mi (2,403.56 km) |
| Grosse Pointe Woods to Orinda (California) | 2,079.12 mi (3,346.02 km) |
| Grosse Pointe Woods to Orland Park (Illinois) | 261.07 mi (420.16 km) |
| Grosse Pointe Woods to Orlando (Florida) | 968.44 mi (1,558.55 km) |
| Grosse Pointe Woods to Ormond Beach (Florida) | 913.25 mi (1,469.74 km) |
| Grosse Pointe Woods to Oro Valley (Arizona) | 1,678.63 mi (2,701.49 km) |
| Grosse Pointe Woods to Oroville (California) | 2,009.85 mi (3,234.55 km) |
| Grosse Pointe Woods to Oshkosh (Wisconsin) | 305.35 mi (491.42 km) |
| Grosse Pointe Woods to Oskaloosa (Iowa) | 507.17 mi (816.21 km) |
