| Greenville to Olympia Heights (Florida) | 640.99 mi (1,031.57 km) |
| Greenville to Omaha (Nebraska) | 865.59 mi (1,393.03 km) |
| Greenville to On Top of the World Designated Place (Florida) | 395.90 mi (637.14 km) |
| Greenville to Onalaska (Wisconsin) | 782.82 mi (1,259.83 km) |
| Greenville to Oneida (New York) | 673.21 mi (1,083.43 km) |
| Greenville to Oneonta (New York) | 656.90 mi (1,057.18 km) |
| Greenville to Ontario (California) | 1,998.58 mi (3,216.40 km) |
| Greenville to Ontario (Oregon) | 1,936.57 mi (3,116.60 km) |
| Greenville to Opa-locka (Florida) | 630.02 mi (1,013.92 km) |
| Greenville to Opelika (Alabama) | 229.14 mi (368.76 km) |
| Greenville to Opelousas (Louisiana) | 638.33 mi (1,027.29 km) |
| Greenville to Orange (California) | 2,014.02 mi (3,241.26 km) |
| Greenville to Orange (Texas) | 739.10 mi (1,189.47 km) |
| Greenville to Orange City (Florida) | 412.55 mi (663.93 km) |
| Greenville to Orangeburg (South Carolina) | 126.23 mi (203.15 km) |
