| Greensboro to Southern Pines (North Carolina) | 66.76 mi (107.43 km) |
| Greensboro to Southfield (Michigan) | 477.47 mi (768.41 km) |
| Greensboro to Southgate (Michigan) | 459.18 mi (738.97 km) |
| Greensboro to Southlake (Texas) | 1,008.24 mi (1,622.60 km) |
| Greensboro to Spanaway (Washington) | 2,295.95 mi (3,694.98 km) |
| Greensboro to Spanish Fork (Utah) | 1,742.28 mi (2,803.94 km) |
| Greensboro to Spanish Lake (Missouri) | 598.67 mi (963.47 km) |
| Greensboro to Spanish Springs (Nevada) | 2,168.96 mi (3,490.60 km) |
| Greensboro to Sparks (Nevada) | 2,172.07 mi (3,495.61 km) |
| Greensboro to Spartanburg (South Carolina) | 142.29 mi (229.00 km) |
| Greensboro to Spearfish (South Dakota) | 1,384.12 mi (2,227.53 km) |
| Greensboro to Speedway (Indiana) | 433.04 mi (696.91 km) |
| Greensboro to Spencer (Iowa) | 947.89 mi (1,525.49 km) |
| Greensboro to Spokane (Washington) | 2,068.14 mi (3,328.35 km) |
| Greensboro to Spokane Valley (Washington) | 2,058.97 mi (3,313.60 km) |
