| Great Driffield to Spello | 966.12 mi (1,554.82 km) |
| Great Driffield to Spilamberto | 831.50 mi (1,338.17 km) |
| Great Driffield to Spilimbergo | 800.95 mi (1,289.00 km) |
| Great Driffield to Spinea | 811.46 mi (1,305.92 km) |
| Great Driffield to Spoleto | 979.92 mi (1,577.02 km) |
| Great Driffield to Spoltore | 1,038.47 mi (1,671.25 km) |
| Great Driffield to Spresiano | 798.75 mi (1,285.47 km) |
| Great Driffield to Squinzano | 1,269.89 mi (2,043.69 km) |
| Great Driffield to Statte | 1,236.28 mi (1,989.59 km) |
| Great Driffield to Stezzano | 730.27 mi (1,175.25 km) |
| Great Driffield to Strada | 894.60 mi (1,439.72 km) |
| Great Driffield to Stradella | 753.88 mi (1,213.26 km) |
| Great Driffield to Striano | 1,145.04 mi (1,842.76 km) |
| Great Driffield to Subiaco | 1,039.26 mi (1,672.53 km) |
| Great Driffield to Sulmona | 1,055.59 mi (1,698.81 km) |
