| Garden Grove to Southern Pines (North Carolina) | 2,184.20 mi (3,515.13 km) |
| Garden Grove to Southfield (Michigan) | 1,963.75 mi (3,160.36 km) |
| Garden Grove to Southgate (Michigan) | 1,964.60 mi (3,161.72 km) |
| Garden Grove to Southlake (Texas) | 1,200.13 mi (1,931.43 km) |
| Garden Grove to Spanaway (Washington) | 949.30 mi (1,527.76 km) |
| Garden Grove to Spanish Fork (Utah) | 559.26 mi (900.04 km) |
| Garden Grove to Spanish Lake (Missouri) | 1,577.48 mi (2,538.70 km) |
| Garden Grove to Spanish Springs (Nevada) | 417.00 mi (671.10 km) |
| Garden Grove to Sparks (Nevada) | 412.02 mi (663.08 km) |
| Garden Grove to Spartanburg (South Carolina) | 2,045.72 mi (3,292.27 km) |
| Garden Grove to Spearfish (South Dakota) | 1,056.54 mi (1,700.34 km) |
| Garden Grove to Speedway (Indiana) | 1,793.26 mi (2,885.97 km) |
| Garden Grove to Spencer (Iowa) | 1,386.98 mi (2,232.13 km) |
| Garden Grove to Spokane (Washington) | 959.99 mi (1,544.95 km) |
| Garden Grove to Spokane Valley (Washington) | 960.02 mi (1,545.01 km) |
