| Galveston to Southern Pines (North Carolina) | 992.57 mi (1,597.38 km) |
| Galveston to Southfield (Michigan) | 1,119.88 mi (1,802.28 km) |
| Galveston to Southgate (Michigan) | 1,107.16 mi (1,781.80 km) |
| Galveston to Southlake (Texas) | 288.82 mi (464.81 km) |
| Galveston to Spanaway (Washington) | 1,920.63 mi (3,090.95 km) |
| Galveston to Spanish Fork (Utah) | 1,208.37 mi (1,944.68 km) |
| Galveston to Spanish Lake (Missouri) | 711.35 mi (1,144.80 km) |
| Galveston to Spanish Springs (Nevada) | 1,576.95 mi (2,537.86 km) |
| Galveston to Sparks (Nevada) | 1,577.39 mi (2,538.56 km) |
| Galveston to Spartanburg (South Carolina) | 853.90 mi (1,374.22 km) |
| Galveston to Spearfish (South Dakota) | 1,161.21 mi (1,868.79 km) |
| Galveston to Speedway (Indiana) | 878.16 mi (1,413.26 km) |
| Galveston to Spencer (Iowa) | 960.40 mi (1,545.61 km) |
| Galveston to Spokane (Washington) | 1,749.92 mi (2,816.22 km) |
| Galveston to Spokane Valley (Washington) | 1,742.52 mi (2,804.31 km) |
