| Galveston to Scottsboro (Alabama) | 638.07 mi (1,026.88 km) |
| Galveston to Scottsdale (Arizona) | 1,044.79 mi (1,681.43 km) |
| Galveston to Scranton (Pennsylvania) | 1,365.76 mi (2,197.97 km) |
| Galveston to Seabrook (Maryland) | 1,228.13 mi (1,976.48 km) |
| Galveston to Seabrook (Texas) | 23.93 mi (38.52 km) |
| Galveston to Seaford (New York) | 1,439.87 mi (2,317.24 km) |
| Galveston to Seagoville (Texas) | 254.83 mi (410.11 km) |
| Galveston to Seal Beach (California) | 1,397.36 mi (2,248.83 km) |
| Galveston to Searcy (Arkansas) | 453.24 mi (729.42 km) |
| Galveston to Seaside (California) | 1,636.15 mi (2,633.12 km) |
| Galveston to SeaTac (Washington) | 1,927.74 mi (3,102.40 km) |
| Galveston to Seattle (Washington) | 1,935.06 mi (3,114.18 km) |
| Galveston to Sebastian (Florida) | 880.09 mi (1,416.37 km) |
| Galveston to Sebring (Florida) | 825.67 mi (1,328.79 km) |
| Galveston to Secaucus (New Jersey) | 1,416.69 mi (2,279.94 km) |
