| Gainesville to University Place (Washington) | 2,452.62 mi (3,947.12 km) |
| Gainesville to Upland (California) | 2,083.66 mi (3,353.32 km) |
| Gainesville to Upper Arlington (Ohio) | 716.07 mi (1,152.40 km) |
| Gainesville to Upper Grand Lagoon (Florida) | 206.06 mi (331.63 km) |
| Gainesville to Upper Montclair (New Jersey) | 896.80 mi (1,443.26 km) |
| Gainesville to Urbana (Illinois) | 792.80 mi (1,275.89 km) |
| Gainesville to Urbana (Maryland) | 724.55 mi (1,166.04 km) |
| Gainesville to Urbana (Ohio) | 724.89 mi (1,166.59 km) |
| Gainesville to Urbandale (Iowa) | 1,044.28 mi (1,680.61 km) |
| Gainesville to Utica (New York) | 1,007.02 mi (1,620.64 km) |
| Gainesville to Uvalde (Texas) | 1,048.35 mi (1,687.15 km) |
| Gainesville to Vacaville (California) | 2,327.77 mi (3,746.19 km) |
| Gainesville to Vadnais Heights (Minnesota) | 1,212.31 mi (1,951.02 km) |
| Gainesville to Vail (Arizona) | 1,684.45 mi (2,710.87 km) |
| Gainesville to Valdosta (Georgia) | 98.14 mi (157.94 km) |
