| Gainesville to St. Simons (Georgia) | 118.20 mi (190.23 km) |
| Gainesville to Stafford (Texas) | 793.33 mi (1,276.74 km) |
| Gainesville to Stallings (North Carolina) | 387.73 mi (623.99 km) |
| Gainesville to Stamford (Connecticut) | 930.46 mi (1,497.42 km) |
| Gainesville to Stanford (California) | 2,336.39 mi (3,760.06 km) |
| Gainesville to Stanton (California) | 2,103.41 mi (3,385.11 km) |
| Gainesville to Star (Idaho) | 2,105.01 mi (3,387.68 km) |
| Gainesville to Starkville (Mississippi) | 462.33 mi (744.05 km) |
| Gainesville to State College (Pennsylvania) | 808.07 mi (1,300.46 km) |
| Gainesville to Staten Island (New York) | 883.33 mi (1,421.58 km) |
| Gainesville to Statesboro (Georgia) | 193.47 mi (311.36 km) |
| Gainesville to Statesville (North Carolina) | 430.33 mi (692.56 km) |
| Gainesville to Staunton (Virginia) | 615.24 mi (990.13 km) |
| Gainesville to Steamboat Springs (Colorado) | 1,564.74 mi (2,518.20 km) |
| Gainesville to Steiner Ranch (Texas) | 930.72 mi (1,497.86 km) |
