| Gainesville to Smyrna (Delaware) | 766.49 mi (1,233.55 km) |
| Gainesville to Smyrna (Georgia) | 315.87 mi (508.34 km) |
| Gainesville to Smyrna (Tennessee) | 497.54 mi (800.72 km) |
| Gainesville to Snellville (Georgia) | 304.50 mi (490.04 km) |
| Gainesville to Snoqualmie (Washington) | 2,426.70 mi (3,905.40 km) |
| Gainesville to Snyder (Texas) | 1,115.56 mi (1,795.32 km) |
| Gainesville to Socastee (South Carolina) | 339.27 mi (546.00 km) |
| Gainesville to Socorro (Texas) | 1,424.92 mi (2,293.18 km) |
| Gainesville to Soddy-Daisy (Tennessee) | 419.04 mi (674.38 km) |
| Gainesville to Solana Beach (California) | 2,063.55 mi (3,320.96 km) |
| Gainesville to Soledad (California) | 2,289.92 mi (3,685.27 km) |
| Gainesville to Solon (Ohio) | 810.40 mi (1,304.21 km) |
| Gainesville to Somers Point (New Jersey) | 797.69 mi (1,283.75 km) |
| Gainesville to Somerset (Kentucky) | 527.87 mi (849.53 km) |
| Gainesville to Somerset (New Jersey) | 868.81 mi (1,398.22 km) |
