| Gainesville to Silver Firs (Washington) | 2,446.93 mi (3,937.96 km) |
| Gainesville to Silver Spring (Maryland) | 711.81 mi (1,145.54 km) |
| Gainesville to Silver Springs Shores (Florida) | 44.00 mi (70.81 km) |
| Gainesville to Silverdale (Washington) | 2,467.01 mi (3,970.27 km) |
| Gainesville to Silverton (Oregon) | 2,428.11 mi (3,907.67 km) |
| Gainesville to Simi Valley (California) | 2,145.57 mi (3,452.96 km) |
| Gainesville to Simpsonville (South Carolina) | 348.84 mi (561.41 km) |
| Gainesville to Sioux City (Iowa) | 1,179.50 mi (1,898.22 km) |
| Gainesville to Sioux Falls (South Dakota) | 1,242.59 mi (1,999.75 km) |
| Gainesville to Skokie (Illinois) | 905.04 mi (1,456.52 km) |
| Gainesville to Sleepy Hollow (New York) | 920.68 mi (1,481.68 km) |
| Gainesville to Slidell (Louisiana) | 446.97 mi (719.32 km) |
| Gainesville to Smithfield (North Carolina) | 465.22 mi (748.69 km) |
| Gainesville to Smithfield (Utah) | 1,841.27 mi (2,963.24 km) |
| Gainesville to Smithville (Missouri) | 965.03 mi (1,553.07 km) |
