| Gainesville to Seymour (Tennessee) | 436.10 mi (701.83 km) |
| Gainesville to Shady Hills (Florida) | 89.01 mi (143.24 km) |
| Gainesville to Shafter (California) | 2,169.97 mi (3,492.23 km) |
| Gainesville to Shaker Heights (Ohio) | 816.10 mi (1,313.39 km) |
| Gainesville to Shakopee (Minnesota) | 1,206.76 mi (1,942.10 km) |
| Gainesville to Sharon (Pennsylvania) | 804.95 mi (1,295.44 km) |
| Gainesville to Sharonville (Ohio) | 673.69 mi (1,084.20 km) |
| Gainesville to Shasta Lake (California) | 2,361.79 mi (3,800.94 km) |
| Gainesville to Shawnee (Kansas) | 958.16 mi (1,542.01 km) |
| Gainesville to Shawnee (Oklahoma) | 936.26 mi (1,506.77 km) |
| Gainesville to Sheboygan (Wisconsin) | 1,015.62 mi (1,634.48 km) |
| Gainesville to Shelby (North Carolina) | 390.41 mi (628.30 km) |
| Gainesville to Shelbyville (Indiana) | 708.18 mi (1,139.70 km) |
| Gainesville to Shelbyville (Kentucky) | 611.75 mi (984.52 km) |
| Gainesville to Shelbyville (Tennessee) | 467.57 mi (752.48 km) |
