| Gainesville to Santa Rosa (California) | 2,368.04 mi (3,810.99 km) |
| Gainesville to Santaquin (Utah) | 1,804.57 mi (2,904.17 km) |
| Gainesville to Santee (California) | 2,048.32 mi (3,296.45 km) |
| Gainesville to Sapulpa (Oklahoma) | 909.02 mi (1,462.92 km) |
| Gainesville to Saraland (Alabama) | 352.71 mi (567.63 km) |
| Gainesville to Sarasota (Florida) | 162.24 mi (261.10 km) |
| Gainesville to Sarasota Springs (Florida) | 164.05 mi (264.02 km) |
| Gainesville to Saratoga (California) | 2,328.42 mi (3,747.23 km) |
| Gainesville to Saratoga Springs (New York) | 1,039.17 mi (1,672.39 km) |
| Gainesville to Saratoga Springs (Utah) | 1,817.16 mi (2,924.44 km) |
| Gainesville to Sartell (Minnesota) | 1,275.36 mi (2,052.49 km) |
| Gainesville to Satellite Beach (Florida) | 147.97 mi (238.13 km) |
| Gainesville to Sauk Rapids (Minnesota) | 1,272.35 mi (2,047.66 km) |
| Gainesville to Sault Ste. Marie (Michigan) | 1,165.97 mi (1,876.45 km) |
| Gainesville to Savage (Minnesota) | 1,202.50 mi (1,935.24 km) |
