| Gainesville to Oswego (Illinois) | 894.29 mi (1,439.22 km) |
| Gainesville to Oswego (New York) | 1,004.59 mi (1,616.72 km) |
| Gainesville to Otsego (Minnesota) | 1,238.88 mi (1,993.79 km) |
| Gainesville to Ottawa (Illinois) | 884.49 mi (1,423.44 km) |
| Gainesville to Ottawa (Kansas) | 960.27 mi (1,545.40 km) |
| Gainesville to Ottumwa (Iowa) | 965.97 mi (1,554.58 km) |
| Gainesville to Overland (Missouri) | 772.78 mi (1,243.68 km) |
| Gainesville to Overland Park (Kansas) | 947.55 mi (1,524.93 km) |
| Gainesville to Overlea (Maryland) | 746.39 mi (1,201.19 km) |
| Gainesville to Oviedo (Florida) | 99.38 mi (159.94 km) |
| Gainesville to Owasso (Oklahoma) | 903.82 mi (1,454.55 km) |
| Gainesville to Owatonna (Minnesota) | 1,160.91 mi (1,868.31 km) |
| Gainesville to Owensboro (Kentucky) | 621.55 mi (1,000.30 km) |
| Gainesville to Owings Mills (Maryland) | 742.55 mi (1,195.02 km) |
| Gainesville to Owosso (Michigan) | 925.54 mi (1,489.51 km) |
