| Gainesville to Orangevale (California) | 2,288.80 mi (3,683.47 km) |
| Gainesville to Orchards (Washington) | 2,426.40 mi (3,904.91 km) |
| Gainesville to Orcutt (California) | 2,239.51 mi (3,604.14 km) |
| Gainesville to Oregon (Ohio) | 829.41 mi (1,334.80 km) |
| Gainesville to Oregon (Wisconsin) | 994.69 mi (1,600.80 km) |
| Gainesville to Oregon City (Oregon) | 2,424.05 mi (3,901.13 km) |
| Gainesville to Orem (Utah) | 1,805.33 mi (2,905.41 km) |
| Gainesville to Orinda (California) | 2,337.91 mi (3,762.50 km) |
| Gainesville to Orland Park (Illinois) | 879.85 mi (1,415.98 km) |
| Gainesville to Orlando (Florida) | 103.06 mi (165.86 km) |
| Gainesville to Ormond Beach (Florida) | 79.36 mi (127.72 km) |
| Gainesville to Oro Valley (Arizona) | 1,700.21 mi (2,736.22 km) |
| Gainesville to Oroville (California) | 2,311.33 mi (3,719.72 km) |
| Gainesville to Oshkosh (Wisconsin) | 1,048.05 mi (1,686.67 km) |
| Gainesville to Oskaloosa (Iowa) | 987.88 mi (1,589.83 km) |
