| Gainesville to Elyria (Ohio) | 808.20 mi (1,300.67 km) |
| Gainesville to Emeryville (California) | 2,344.04 mi (3,772.37 km) |
| Gainesville to Emmaus (Pennsylvania) | 843.29 mi (1,357.15 km) |
| Gainesville to Emporia (Kansas) | 993.92 mi (1,599.56 km) |
| Gainesville to Encinitas (California) | 2,063.55 mi (3,320.96 km) |
| Gainesville to Endicott (New York) | 926.54 mi (1,491.12 km) |
| Gainesville to Endwell (New York) | 928.71 mi (1,494.62 km) |
| Gainesville to Englewood (Colorado) | 1,453.81 mi (2,339.68 km) |
| Gainesville to Englewood (Florida) | 187.15 mi (301.19 km) |
| Gainesville to Englewood (New Jersey) | 906.14 mi (1,458.29 km) |
| Gainesville to Englewood (Ohio) | 712.33 mi (1,146.39 km) |
| Gainesville to Enid (Oklahoma) | 1,010.35 mi (1,625.99 km) |
| Gainesville to Ennis (Texas) | 865.01 mi (1,392.09 km) |
| Gainesville to Ensley (Florida) | 300.24 mi (483.19 km) |
| Gainesville to Enterprise (Alabama) | 237.41 mi (382.08 km) |
