| Fruita to Southern Pines (North Carolina) | 1,630.28 mi (2,623.68 km) |
| Fruita to Southfield (Michigan) | 1,346.22 mi (2,166.53 km) |
| Fruita to Southgate (Michigan) | 1,348.75 mi (2,170.61 km) |
| Fruita to Southlake (Texas) | 774.85 mi (1,247.01 km) |
| Fruita to Spanaway (Washington) | 879.85 mi (1,415.99 km) |
| Fruita to Spanish Fork (Utah) | 168.32 mi (270.88 km) |
| Fruita to Spanish Lake (Missouri) | 993.59 mi (1,599.02 km) |
| Fruita to Spanish Springs (Nevada) | 584.65 mi (940.91 km) |
| Fruita to Sparks (Nevada) | 587.18 mi (944.97 km) |
| Fruita to Spartanburg (South Carolina) | 1,500.77 mi (2,415.26 km) |
| Fruita to Spearfish (South Dakota) | 446.99 mi (719.36 km) |
| Fruita to Speedway (Indiana) | 1,196.73 mi (1,925.96 km) |
| Fruita to Spencer (Iowa) | 757.20 mi (1,218.59 km) |
| Fruita to Spokane (Washington) | 731.60 mi (1,177.40 km) |
| Fruita to Spokane Valley (Washington) | 725.51 mi (1,167.59 km) |
