| Friendswood to Storm Lake (Iowa) | 907.34 mi (1,460.22 km) |
| Friendswood to Storrs (Connecticut) | 1,535.40 mi (2,470.99 km) |
| Friendswood to Stoughton (Wisconsin) | 984.08 mi (1,583.73 km) |
| Friendswood to Stow (Ohio) | 1,115.87 mi (1,795.82 km) |
| Friendswood to Streamwood (Illinois) | 948.87 mi (1,527.06 km) |
| Friendswood to Streator (Illinois) | 878.42 mi (1,413.68 km) |
| Friendswood to Streetsboro (Ohio) | 1,122.22 mi (1,806.04 km) |
| Friendswood to Strongsville (Ohio) | 1,107.05 mi (1,781.63 km) |
| Friendswood to Stuart (Florida) | 922.52 mi (1,484.66 km) |
| Friendswood to Stuarts Draft (Virginia) | 1,096.32 mi (1,764.36 km) |
| Friendswood to Sturgis (Michigan) | 1,009.50 mi (1,624.64 km) |
| Friendswood to Suamico (Wisconsin) | 1,115.34 mi (1,794.97 km) |
| Friendswood to Sudley (Virginia) | 1,194.76 mi (1,922.79 km) |
| Friendswood to Suffern (New York) | 1,426.38 mi (2,295.54 km) |
| Friendswood to Suffolk (Virginia) | 1,180.54 mi (1,899.90 km) |
