| Friendswood to Elyria (Ohio) | 1,099.75 mi (1,769.88 km) |
| Friendswood to Emeryville (California) | 1,653.53 mi (2,661.10 km) |
| Friendswood to Emmaus (Pennsylvania) | 1,345.04 mi (2,164.63 km) |
| Friendswood to Emporia (Kansas) | 616.99 mi (992.95 km) |
| Friendswood to Encinitas (California) | 1,322.96 mi (2,129.10 km) |
| Friendswood to Endicott (New York) | 1,374.92 mi (2,212.71 km) |
| Friendswood to Endwell (New York) | 1,377.49 mi (2,216.85 km) |
| Friendswood to Englewood (Colorado) | 893.75 mi (1,438.35 km) |
| Friendswood to Englewood (Florida) | 800.87 mi (1,288.87 km) |
| Friendswood to Englewood (New Jersey) | 1,427.21 mi (2,296.87 km) |
| Friendswood to Englewood (Ohio) | 944.28 mi (1,519.67 km) |
| Friendswood to Enid (Oklahoma) | 500.90 mi (806.12 km) |
| Friendswood to Ennis (Texas) | 212.28 mi (341.63 km) |
| Friendswood to Ensley (Florida) | 479.16 mi (771.13 km) |
| Friendswood to Enterprise (Alabama) | 570.96 mi (918.87 km) |
