| Fredericksburg to Southern Pines (North Carolina) | 239.42 mi (385.31 km) |
| Fredericksburg to Southfield (Michigan) | 418.87 mi (674.11 km) |
| Fredericksburg to Southgate (Michigan) | 404.48 mi (650.95 km) |
| Fredericksburg to Southlake (Texas) | 1,161.68 mi (1,869.55 km) |
| Fredericksburg to Spanaway (Washington) | 2,326.85 mi (3,744.70 km) |
| Fredericksburg to Spanish Fork (Utah) | 1,821.61 mi (2,931.59 km) |
| Fredericksburg to Spanish Lake (Missouri) | 687.69 mi (1,106.73 km) |
| Fredericksburg to Spanish Springs (Nevada) | 2,246.63 mi (3,615.61 km) |
| Fredericksburg to Sparks (Nevada) | 2,250.21 mi (3,621.37 km) |
| Fredericksburg to Spartanburg (South Carolina) | 338.00 mi (543.95 km) |
| Fredericksburg to Spearfish (South Dakota) | 1,422.94 mi (2,290.00 km) |
| Fredericksburg to Speedway (Indiana) | 481.10 mi (774.26 km) |
| Fredericksburg to Spencer (Iowa) | 981.53 mi (1,579.62 km) |
| Fredericksburg to Spokane (Washington) | 2,093.98 mi (3,369.93 km) |
| Fredericksburg to Spokane Valley (Washington) | 2,084.74 mi (3,355.07 km) |
