| Fredericksburg to Scottsboro (Alabama) | 538.27 mi (866.27 km) |
| Fredericksburg to Scottsdale (Arizona) | 1,936.67 mi (3,116.78 km) |
| Fredericksburg to Scranton (Pennsylvania) | 235.30 mi (378.68 km) |
| Fredericksburg to Seabrook (Maryland) | 58.27 mi (93.78 km) |
| Fredericksburg to Seabrook (Texas) | 1,169.08 mi (1,881.46 km) |
| Fredericksburg to Seaford (New York) | 268.59 mi (432.26 km) |
| Fredericksburg to Seagoville (Texas) | 1,138.50 mi (1,832.24 km) |
| Fredericksburg to Seal Beach (California) | 2,271.14 mi (3,655.04 km) |
| Fredericksburg to Searcy (Arkansas) | 815.43 mi (1,312.30 km) |
| Fredericksburg to Seaside (California) | 2,410.69 mi (3,879.63 km) |
| Fredericksburg to SeaTac (Washington) | 2,320.49 mi (3,734.46 km) |
| Fredericksburg to Seattle (Washington) | 2,321.52 mi (3,736.12 km) |
| Fredericksburg to Sebastian (Florida) | 746.94 mi (1,202.08 km) |
| Fredericksburg to Sebring (Florida) | 782.11 mi (1,258.69 km) |
| Fredericksburg to Secaucus (New Jersey) | 250.23 mi (402.71 km) |
