| Fredericksburg to Enterprise (Nevada) | 2,069.92 mi (3,331.22 km) |
| Fredericksburg to Enumclaw (Washington) | 2,306.32 mi (3,711.66 km) |
| Fredericksburg to Ephrata (Pennsylvania) | 147.61 mi (237.56 km) |
| Fredericksburg to Erie (Colorado) | 1,474.90 mi (2,373.62 km) |
| Fredericksburg to Erie (Pennsylvania) | 296.93 mi (477.87 km) |
| Fredericksburg to Erlanger (Kentucky) | 386.09 mi (621.35 km) |
| Fredericksburg to Escanaba (Michigan) | 711.59 mi (1,145.19 km) |
| Fredericksburg to Escondido (California) | 2,231.89 mi (3,591.88 km) |
| Fredericksburg to Española (New Mexico) | 1,575.65 mi (2,535.76 km) |
| Fredericksburg to Essex (Maryland) | 89.17 mi (143.51 km) |
| Fredericksburg to Essex Junction (Vermont) | 483.92 mi (778.79 km) |
| Fredericksburg to Estelle (Louisiana) | 927.13 mi (1,492.08 km) |
| Fredericksburg to Estero (Florida) | 857.62 mi (1,380.20 km) |
| Fredericksburg to Euclid (Ohio) | 311.88 mi (501.92 km) |
| Fredericksburg to Eufaula (Alabama) | 618.00 mi (994.58 km) |
