| Fredericksburg to Elyria (Ohio) | 324.32 mi (521.94 km) |
| Fredericksburg to Emeryville (California) | 2,412.96 mi (3,883.29 km) |
| Fredericksburg to Emmaus (Pennsylvania) | 187.45 mi (301.68 km) |
| Fredericksburg to Emporia (Kansas) | 1,011.86 mi (1,628.43 km) |
| Fredericksburg to Encinitas (California) | 2,244.20 mi (3,611.69 km) |
| Fredericksburg to Endicott (New York) | 273.00 mi (439.34 km) |
| Fredericksburg to Endwell (New York) | 274.96 mi (442.51 km) |
| Fredericksburg to Englewood (Colorado) | 1,474.72 mi (2,373.34 km) |
| Fredericksburg to Englewood (Florida) | 831.92 mi (1,338.84 km) |
| Fredericksburg to Englewood (New Jersey) | 258.95 mi (416.75 km) |
| Fredericksburg to Englewood (Ohio) | 381.31 mi (613.65 km) |
| Fredericksburg to Enid (Oklahoma) | 1,124.79 mi (1,810.18 km) |
| Fredericksburg to Ennis (Texas) | 1,153.04 mi (1,855.64 km) |
| Fredericksburg to Ensley (Florida) | 773.45 mi (1,244.75 km) |
| Fredericksburg to Enterprise (Alabama) | 675.33 mi (1,086.84 km) |
