| Frederick to Odessa (Texas) | 1,487.76 mi (2,394.32 km) |
| Frederick to Ogden (Utah) | 1,812.24 mi (2,916.51 km) |
| Frederick to Oildale (California) | 2,279.74 mi (3,668.89 km) |
| Frederick to Ojus (Florida) | 944.65 mi (1,520.27 km) |
| Frederick to Okemos (Michigan) | 428.78 mi (690.06 km) |
| Frederick to Oklahoma City (Oklahoma) | 1,133.40 mi (1,824.03 km) |
| Frederick to Okmulgee (Oklahoma) | 1,050.36 mi (1,690.39 km) |
| Frederick to Olathe (Kansas) | 931.85 mi (1,499.67 km) |
| Frederick to Old Jamestown (Missouri) | 690.39 mi (1,111.08 km) |
| Frederick to Oldsmar (Florida) | 842.04 mi (1,355.14 km) |
| Frederick to Olean (New York) | 190.57 mi (306.69 km) |
| Frederick to Olive Branch (Mississippi) | 749.93 mi (1,206.89 km) |
| Frederick to Olivehurst (California) | 2,337.59 mi (3,761.98 km) |
| Frederick to Olney (Maryland) | 27.01 mi (43.46 km) |
| Frederick to Olympia (Washington) | 2,314.57 mi (3,724.94 km) |
