| Frederick to Lewiston (Maine) | 492.63 mi (792.81 km) |
| Frederick to Lewisville (North Carolina) | 282.54 mi (454.70 km) |
| Frederick to Lewisville (Texas) | 1,173.28 mi (1,888.22 km) |
| Frederick to Lexington (Kentucky) | 391.53 mi (630.10 km) |
| Frederick to Lexington (Nebraska) | 1,180.62 mi (1,900.02 km) |
| Frederick to Lexington (North Carolina) | 295.54 mi (475.63 km) |
| Frederick to Lexington (South Carolina) | 431.13 mi (693.83 km) |
| Frederick to Lexington Park (Maryland) | 96.91 mi (155.96 km) |
| Frederick to Liberal (Kansas) | 1,283.04 mi (2,064.85 km) |
| Frederick to Liberty (Missouri) | 907.49 mi (1,460.46 km) |
| Frederick to Liberty Lake (Washington) | 2,042.64 mi (3,287.30 km) |
| Frederick to Liberty Triangle (Florida) | 766.12 mi (1,232.96 km) |
| Frederick to Libertyville (Illinois) | 585.14 mi (941.69 km) |
| Frederick to Lighthouse Point (Florida) | 921.97 mi (1,483.77 km) |
| Frederick to Lilburn (Georgia) | 534.04 mi (859.46 km) |
