| Frederick to Indianola (Iowa) | 858.94 mi (1,382.33 km) |
| Frederick to Indio (California) | 2,172.35 mi (3,496.05 km) |
| Frederick to Inglewood (California) | 2,279.12 mi (3,667.90 km) |
| Frederick to Inkster (Michigan) | 366.07 mi (589.14 km) |
| Frederick to Inver Grove Heights (Minnesota) | 882.06 mi (1,419.54 km) |
| Frederick to Inwood (New York) | 210.47 mi (338.72 km) |
| Frederick to Iona (Florida) | 930.25 mi (1,497.09 km) |
| Frederick to Ionia (Michigan) | 467.09 mi (751.70 km) |
| Frederick to Iowa City (Iowa) | 755.97 mi (1,216.61 km) |
| Frederick to Irmo (South Carolina) | 423.60 mi (681.71 km) |
| Frederick to Irondale (Alabama) | 654.68 mi (1,053.61 km) |
| Frederick to Ironton (Ohio) | 289.44 mi (465.81 km) |
| Frederick to Irvine (California) | 2,255.90 mi (3,630.52 km) |
| Frederick to Irving (Texas) | 1,178.76 mi (1,897.03 km) |
| Frederick to Isabela (Puerto Rico) | 1,574.19 mi (2,533.42 km) |
