| Frederick to Hutchinson (Minnesota) | 944.57 mi (1,520.14 km) |
| Frederick to Hutto (Texas) | 1,290.43 mi (2,076.75 km) |
| Frederick to Hyattsville (Maryland) | 40.87 mi (65.77 km) |
| Frederick to Hybla Valley (Virginia) | 50.59 mi (81.41 km) |
| Frederick to Idaho Falls (Idaho) | 1,801.18 mi (2,898.72 km) |
| Frederick to Idylwood (Virginia) | 39.22 mi (63.12 km) |
| Frederick to Ilchester (Maryland) | 37.58 mi (60.47 km) |
| Frederick to Immokalee (Florida) | 928.12 mi (1,493.66 km) |
| Frederick to Imperial (California) | 2,160.68 mi (3,477.28 km) |
| Frederick to Imperial Beach (California) | 2,250.58 mi (3,621.96 km) |
| Frederick to Independence (Kentucky) | 383.43 mi (617.07 km) |
| Frederick to Independence (Missouri) | 905.02 mi (1,456.48 km) |
| Frederick to Indian Trail (North Carolina) | 349.92 mi (563.13 km) |
| Frederick to Indiana (Pennsylvania) | 123.39 mi (198.58 km) |
| Frederick to Indianapolis (Indiana) | 465.24 mi (748.73 km) |
