| Frederick to Eugene (Oregon) | 2,347.13 mi (3,777.34 km) |
| Frederick to Euless (Texas) | 1,184.62 mi (1,906.47 km) |
| Frederick to Eureka (California) | 2,442.03 mi (3,930.06 km) |
| Frederick to Eureka (Missouri) | 713.26 mi (1,147.89 km) |
| Frederick to Eustis (Florida) | 770.14 mi (1,239.43 km) |
| Frederick to Evans (Colorado) | 1,444.06 mi (2,323.98 km) |
| Frederick to Evans (Georgia) | 482.89 mi (777.13 km) |
| Frederick to Evanston (Illinois) | 567.21 mi (912.83 km) |
| Frederick to Evanston (Wyoming) | 1,760.24 mi (2,832.83 km) |
| Frederick to Evansville (Indiana) | 554.36 mi (892.16 km) |
| Frederick to Everett (Massachusetts) | 390.25 mi (628.05 km) |
| Frederick to Everett (Washington) | 2,277.45 mi (3,665.20 km) |
| Frederick to Evergreen Park (Illinois) | 562.11 mi (904.63 km) |
| Frederick to Ewa Beach (Hawaii) | 4,809.12 mi (7,739.53 km) |
| Frederick to Ewa Gentry (Hawaii) | 4,809.46 mi (7,740.07 km) |
