| Frankfurt to Rothenburg ob der Tauber | 83.76 mi (134.80 km) |
| Frankfurt to Rottweil | 134.24 mi (216.04 km) |
| Frankfurt to Rudersberg | 92.76 mi (149.28 km) |
| Frankfurt to Rudesheim am Rhein | 34.49 mi (55.50 km) |
| Frankfurt to Rudolstadt | 123.77 mi (199.18 km) |
| Frankfurt to Runkel | 30.93 mi (49.78 km) |
| Frankfurt to Ruppichteroth | 73.04 mi (117.55 km) |
| Frankfurt to Russelsheim | 14.41 mi (23.19 km) |
| Frankfurt to Rutesheim | 90.65 mi (145.89 km) |
| Frankfurt to Ruthen | 95.93 mi (154.38 km) |
| Frankfurt to Saalfeld | 124.00 mi (199.56 km) |
| Frankfurt to Saarbrucken | 96.60 mi (155.46 km) |
| Frankfurt to Saarlouis | 102.27 mi (164.59 km) |
| Frankfurt to Saarwellingen | 98.79 mi (158.98 km) |
| Frankfurt to Salzgitter | 158.04 mi (254.34 km) |
