| Francavilla Fontana to Southern Pines (North Carolina) | 5,016.37 mi (8,073.07 km) |
| Francavilla Fontana to Southfield (Michigan) | 4,872.77 mi (7,841.97 km) |
| Francavilla Fontana to Southgate (Michigan) | 4,882.04 mi (7,856.88 km) |
| Francavilla Fontana to Southlake (Texas) | 5,874.78 mi (9,454.54 km) |
| Francavilla Fontana to Spanaway (Washington) | 5,902.65 mi (9,499.39 km) |
| Francavilla Fontana to Spanish Fork (Utah) | 6,015.91 mi (9,681.67 km) |
| Francavilla Fontana to Spanish Lake (Missouri) | 5,315.47 mi (8,554.42 km) |
| Francavilla Fontana to Spanish Springs (Nevada) | 6,277.55 mi (10,102.74 km) |
| Francavilla Fontana to Sparks (Nevada) | 6,283.76 mi (10,112.73 km) |
| Francavilla Fontana to Spartanburg (South Carolina) | 5,138.87 mi (8,270.20 km) |
| Francavilla Fontana to Spearfish (South Dakota) | 5,530.18 mi (8,899.97 km) |
| Francavilla Fontana to Speedway (Indiana) | 5,110.02 mi (8,223.78 km) |
| Francavilla Fontana to Spencer (Iowa) | 5,299.17 mi (8,528.19 km) |
| Francavilla Fontana to Spokane (Washington) | 5,748.56 mi (9,251.41 km) |
| Francavilla Fontana to Spokane Valley (Washington) | 5,743.82 mi (9,243.78 km) |
