| Framingham to Scottsboro (Alabama) | 949.29 mi (1,527.74 km) |
| Framingham to Scottsdale (Arizona) | 2,257.47 mi (3,633.05 km) |
| Framingham to Scranton (Pennsylvania) | 226.35 mi (364.27 km) |
| Framingham to Seabrook (Maryland) | 365.14 mi (587.64 km) |
| Framingham to Seabrook (Texas) | 1,577.28 mi (2,538.38 km) |
| Framingham to Seaford (New York) | 155.45 mi (250.17 km) |
| Framingham to Seagoville (Texas) | 1,522.04 mi (2,449.49 km) |
| Framingham to Seal Beach (California) | 2,572.39 mi (4,139.87 km) |
| Framingham to Searcy (Arkansas) | 1,193.52 mi (1,920.79 km) |
| Framingham to Seaside (California) | 2,676.56 mi (4,307.50 km) |
| Framingham to SeaTac (Washington) | 2,470.41 mi (3,975.73 km) |
| Framingham to Seattle (Washington) | 2,469.28 mi (3,973.93 km) |
| Framingham to Sebastian (Florida) | 1,124.93 mi (1,810.40 km) |
| Framingham to Sebring (Florida) | 1,169.46 mi (1,882.06 km) |
| Framingham to Secaucus (New Jersey) | 172.10 mi (276.96 km) |
