| Framingham to Savannah (Georgia) | 888.83 mi (1,430.43 km) |
| Framingham to Sayreville (New Jersey) | 196.47 mi (316.19 km) |
| Framingham to Sayville (New York) | 137.43 mi (221.17 km) |
| Framingham to Scaggsville (Maryland) | 359.37 mi (578.36 km) |
| Framingham to Scarsdale (New York) | 151.31 mi (243.51 km) |
| Framingham to Schaumburg (Illinois) | 851.34 mi (1,370.09 km) |
| Framingham to Schenectady (New York) | 131.27 mi (211.27 km) |
| Framingham to Schererville (Indiana) | 823.99 mi (1,326.08 km) |
| Framingham to Schertz (Texas) | 1,728.44 mi (2,781.66 km) |
| Framingham to Schiller Park (Illinois) | 841.01 mi (1,353.48 km) |
| Framingham to Schofield Barracks (Hawaii) | 5,065.45 mi (8,152.05 km) |
| Framingham to Scotchtown (New York) | 161.28 mi (259.55 km) |
| Framingham to Scottdale (Georgia) | 910.88 mi (1,465.92 km) |
| Framingham to Scotts Valley (California) | 2,673.96 mi (4,303.32 km) |
| Framingham to Scottsbluff (Nebraska) | 1,642.65 mi (2,643.59 km) |
