| Framingham to Santa Rosa (California) | 2,670.89 mi (4,298.39 km) |
| Framingham to Santaquin (Utah) | 2,086.48 mi (3,357.87 km) |
| Framingham to Santee (California) | 2,545.88 mi (4,097.19 km) |
| Framingham to Sapulpa (Oklahoma) | 1,385.38 mi (2,229.55 km) |
| Framingham to Saraland (Alabama) | 1,213.32 mi (1,952.65 km) |
| Framingham to Sarasota (Florida) | 1,208.58 mi (1,945.03 km) |
| Framingham to Sarasota Springs (Florida) | 1,208.42 mi (1,944.77 km) |
| Framingham to Saratoga (California) | 2,668.74 mi (4,294.92 km) |
| Framingham to Saratoga Springs (New York) | 129.92 mi (209.09 km) |
| Framingham to Saratoga Springs (Utah) | 2,084.81 mi (3,355.18 km) |
| Framingham to Sartell (Minnesota) | 1,151.80 mi (1,853.64 km) |
| Framingham to Satellite Beach (Florida) | 1,103.21 mi (1,775.44 km) |
| Framingham to Sauk Rapids (Minnesota) | 1,148.49 mi (1,848.32 km) |
| Framingham to Sault Ste. Marie (Michigan) | 699.59 mi (1,125.88 km) |
| Framingham to Savage (Minnesota) | 1,107.80 mi (1,782.83 km) |
