| Framingham to Orangevale (California) | 2,590.26 mi (4,168.61 km) |
| Framingham to Orchards (Washington) | 2,506.88 mi (4,034.43 km) |
| Framingham to Orcutt (California) | 2,657.53 mi (4,276.88 km) |
| Framingham to Oregon (Ohio) | 617.25 mi (993.38 km) |
| Framingham to Oregon (Wisconsin) | 912.06 mi (1,467.82 km) |
| Framingham to Oregon City (Oregon) | 2,515.48 mi (4,048.27 km) |
| Framingham to Orem (Utah) | 2,074.90 mi (3,339.23 km) |
| Framingham to Orinda (California) | 2,659.60 mi (4,280.21 km) |
| Framingham to Orland Park (Illinois) | 844.00 mi (1,358.29 km) |
| Framingham to Orlando (Florida) | 1,104.60 mi (1,777.68 km) |
| Framingham to Ormond Beach (Florida) | 1,047.78 mi (1,686.25 km) |
| Framingham to Oro Valley (Arizona) | 2,253.54 mi (3,626.72 km) |
| Framingham to Oroville (California) | 2,586.84 mi (4,163.12 km) |
| Framingham to Oshkosh (Wisconsin) | 869.50 mi (1,399.33 km) |
| Framingham to Oskaloosa (Iowa) | 1,091.56 mi (1,756.70 km) |
