| Framingham to Olympia Heights (Florida) | 1,252.39 mi (2,015.52 km) |
| Framingham to Omaha (Nebraska) | 1,265.83 mi (2,037.16 km) |
| Framingham to On Top of the World Designated Place (Florida) | 1,094.58 mi (1,761.56 km) |
| Framingham to Onalaska (Wisconsin) | 1,000.98 mi (1,610.91 km) |
| Framingham to Oneida (New York) | 221.02 mi (355.70 km) |
| Framingham to Oneonta (New York) | 185.52 mi (298.56 km) |
| Framingham to Ontario (California) | 2,539.68 mi (4,087.22 km) |
| Framingham to Ontario (Oregon) | 2,268.56 mi (3,650.89 km) |
| Framingham to Opa-locka (Florida) | 1,239.18 mi (1,994.27 km) |
| Framingham to Opelika (Alabama) | 1,011.71 mi (1,628.18 km) |
| Framingham to Opelousas (Louisiana) | 1,401.11 mi (2,254.87 km) |
| Framingham to Orange (California) | 2,558.08 mi (4,116.83 km) |
| Framingham to Orange (Texas) | 1,495.10 mi (2,406.14 km) |
| Framingham to Orange City (Florida) | 1,075.25 mi (1,730.46 km) |
| Framingham to Orangeburg (South Carolina) | 796.02 mi (1,281.07 km) |
