| Framingham to Enterprise (Nevada) | 2,359.49 mi (3,797.23 km) |
| Framingham to Enumclaw (Washington) | 2,459.43 mi (3,958.06 km) |
| Framingham to Ephrata (Pennsylvania) | 286.91 mi (461.74 km) |
| Framingham to Erie (Colorado) | 1,743.23 mi (2,805.46 km) |
| Framingham to Erie (Pennsylvania) | 441.98 mi (711.29 km) |
| Framingham to Erlanger (Kentucky) | 725.00 mi (1,166.78 km) |
| Framingham to Escanaba (Michigan) | 811.57 mi (1,306.10 km) |
| Framingham to Escondido (California) | 2,541.22 mi (4,089.70 km) |
| Framingham to Española (New Mexico) | 1,891.96 mi (3,044.82 km) |
| Framingham to Essex (Maryland) | 334.19 mi (537.82 km) |
| Framingham to Essex Junction (Vermont) | 172.65 mi (277.86 km) |
| Framingham to Estelle (Louisiana) | 1,346.69 mi (2,167.28 km) |
| Framingham to Estero (Florida) | 1,243.90 mi (2,001.86 km) |
| Framingham to Euclid (Ohio) | 520.15 mi (837.10 km) |
| Framingham to Eufaula (Alabama) | 1,040.14 mi (1,673.95 km) |
