| Framingham to Elyria (Ohio) | 552.57 mi (889.28 km) |
| Framingham to Emeryville (California) | 2,666.49 mi (4,291.29 km) |
| Framingham to Emmaus (Pennsylvania) | 243.44 mi (391.77 km) |
| Framingham to Emporia (Kansas) | 1,326.12 mi (2,134.19 km) |
| Framingham to Encinitas (California) | 2,553.64 mi (4,109.69 km) |
| Framingham to Endicott (New York) | 237.24 mi (381.80 km) |
| Framingham to Endwell (New York) | 234.98 mi (378.16 km) |
| Framingham to Englewood (Colorado) | 1,748.69 mi (2,814.24 km) |
| Framingham to Englewood (Florida) | 1,225.53 mi (1,972.31 km) |
| Framingham to Englewood (New Jersey) | 163.58 mi (263.25 km) |
| Framingham to Englewood (Ohio) | 690.44 mi (1,111.15 km) |
| Framingham to Enid (Oklahoma) | 1,463.14 mi (2,354.69 km) |
| Framingham to Ennis (Texas) | 1,538.87 mi (2,476.57 km) |
| Framingham to Ensley (Florida) | 1,195.45 mi (1,923.89 km) |
| Framingham to Enterprise (Alabama) | 1,097.48 mi (1,766.22 km) |
