| Four Corners to Elyria (Ohio) | 2,052.55 mi (3,303.26 km) |
| Four Corners to Emeryville (California) | 491.19 mi (790.49 km) |
| Four Corners to Emmaus (Pennsylvania) | 2,393.84 mi (3,852.51 km) |
| Four Corners to Emporia (Kansas) | 1,446.19 mi (2,327.41 km) |
| Four Corners to Encinitas (California) | 875.68 mi (1,409.27 km) |
| Four Corners to Endicott (New York) | 2,325.73 mi (3,742.91 km) |
| Four Corners to Endwell (New York) | 2,327.23 mi (3,745.32 km) |
| Four Corners to Englewood (Colorado) | 986.14 mi (1,587.04 km) |
| Four Corners to Englewood (Florida) | 2,552.45 mi (4,107.77 km) |
| Four Corners to Englewood (New Jersey) | 2,457.38 mi (3,954.77 km) |
| Four Corners to Englewood (Ohio) | 1,984.37 mi (3,193.54 km) |
| Four Corners to Enid (Oklahoma) | 1,433.67 mi (2,307.27 km) |
| Four Corners to Ennis (Texas) | 1,655.79 mi (2,664.74 km) |
| Four Corners to Ensley (Florida) | 2,166.35 mi (3,486.41 km) |
| Four Corners to Enterprise (Alabama) | 2,201.10 mi (3,542.32 km) |
