| Fort Pierce to Superior (Colorado) | 1,659.47 mi (2,670.67 km) |
| Fort Pierce to Superior (Wisconsin) | 1,476.51 mi (2,376.21 km) |
| Fort Pierce to Surprise (Arizona) | 1,950.39 mi (3,138.84 km) |
| Fort Pierce to Susanville (California) | 2,451.95 mi (3,946.03 km) |
| Fort Pierce to Sussex (Wisconsin) | 1,171.49 mi (1,885.33 km) |
| Fort Pierce to Suwanee (Georgia) | 508.31 mi (818.05 km) |
| Fort Pierce to Swansea (Illinois) | 949.06 mi (1,527.37 km) |
| Fort Pierce to Sweetwater (Florida) | 113.81 mi (183.17 km) |
| Fort Pierce to Sweetwater (Texas) | 1,248.62 mi (2,009.46 km) |
| Fort Pierce to Sycamore (Illinois) | 1,111.17 mi (1,788.25 km) |
| Fort Pierce to Sylacauga (Alabama) | 531.36 mi (855.13 km) |
| Fort Pierce to Sylvania (Ohio) | 1,005.14 mi (1,617.62 km) |
| Fort Pierce to Syosset (New York) | 1,003.67 mi (1,615.25 km) |
| Fort Pierce to Syracuse (New York) | 1,104.23 mi (1,777.09 km) |
| Fort Pierce to Syracuse (Utah) | 2,027.10 mi (3,262.31 km) |
