| Fort Pierce to Storm Lake (Iowa) | 1,341.63 mi (2,159.15 km) |
| Fort Pierce to Storrs (Connecticut) | 1,093.81 mi (1,760.32 km) |
| Fort Pierce to Stoughton (Wisconsin) | 1,180.74 mi (1,900.21 km) |
| Fort Pierce to Stow (Ohio) | 952.12 mi (1,532.29 km) |
| Fort Pierce to Streamwood (Illinois) | 1,101.00 mi (1,771.89 km) |
| Fort Pierce to Streator (Illinois) | 1,062.00 mi (1,709.12 km) |
| Fort Pierce to Streetsboro (Ohio) | 956.15 mi (1,538.78 km) |
| Fort Pierce to Strongsville (Ohio) | 963.22 mi (1,550.16 km) |
| Fort Pierce to Stuart (Florida) | 16.98 mi (27.33 km) |
| Fort Pierce to Stuarts Draft (Virginia) | 735.84 mi (1,184.22 km) |
| Fort Pierce to Sturgis (Michigan) | 1,033.68 mi (1,663.55 km) |
| Fort Pierce to Suamico (Wisconsin) | 1,263.53 mi (2,033.46 km) |
| Fort Pierce to Sudley (Virginia) | 802.04 mi (1,290.75 km) |
| Fort Pierce to Suffern (New York) | 1,009.14 mi (1,624.06 km) |
| Fort Pierce to Suffolk (Virginia) | 676.03 mi (1,087.96 km) |
